Molecular and Cell Biology

Immunology Professor Jennifer Manilay and bioengineering Professor Joel Spencer are using a new grant from the National Institutes of Health (NIH) to expand a project they’ve been working on for the past two years — delving into the immune systems of living mice to see how B-cells develop under different circumstances.

From graduate student Jose Zamora’s perspective, the CREST Center for Cellular and Biomolecular Machines (CCBM) has been a spectacular success.

A brand-new faculty member is shaking up the way researchers understand cellular systems.

Computational biology Professor Bercem Dutagaci, who started at UC Merced in January, developed simulations of bacterial cells as a new way of looking at how RNA and proteins self-organize inside the cells. Her most recent work demonstrates that the insides of cells are organized at complex levels of order, instead of a chaotic stew of molecules.

About 35 percent of Americans have metabolic syndrome, a group of risk factors that raises the risk of cardiovascular disease — the leading cause of death in the United States.

If you have three of these five issues, you have metabolic syndrome, according to the American Heart Association:

Molecular biology Professor Chris Amemiya and his former graduate student Molly Phillips have made a discovery that upends traditional ideas about a structural polysaccharide called chitin that is found in some fish.

Having had the common cold appears to have programmed some people’s immune cells to recognize the coronavirus that causes COVID-19.

That discovery — by an immunology team that includes a UC Merced alumnus — could change scientists’ understanding of the virus behind the current pandemic.

Maybe now more than ever, scientists need to understand the immune system.

A new National Institutes of Health grant is funding a cross-disciplinary collaboration between bioengineering Professor Joel Spencer and immunology Professor Jennifer Manilay that will allow them to watch as immune-system cells develop in the bone marrow of a living mouse to gain insights into how they work.

Many of the items people use in their everyday lives, from baby clothes and Halloween costumes to furniture, are doused with chemical flame retardants designed to make the items safer.

A UC Merced researcher and her lab have unlocked one of the mysteries that could lead to treatments — or even cures — for prion diseases in mammals.

Prion diseases are a family of rare, progressive neurodegenerative disorders that affect both humans — such as with Creutzfeldt-Jakob disease or fatal familial insomnia — and animals, such as mad-cow disease. These disorders are usually rapidly progressive and always fatal, according to the Centers for Disease Control.

Breakthrough collaborative science by an interdisciplinary team of researchers brought together by computational biology Professor David Ardell promises a new approach for treating all types of infections.

Infections have become more dangerous in recent years because bacteria and parasites rapidly evolve resistance to the medicines.