Health Sciences Research Institute

Maybe now more than ever, scientists need to understand the immune system.

A new National Institutes of Health grant is funding a cross-disciplinary collaboration between bioengineering Professor Joel Spencer and immunology Professor Jennifer Manilay that will allow them to watch as immune-system cells develop in the bone marrow of a living mouse to gain insights into how they work.

Many of the items people use in their everyday lives, from baby clothes and Halloween costumes to furniture, are doused with chemical flame retardants designed to make the items safer.

Professor Matthew Zawadzki is with the Department of Psychological Sciences in the School of Social Sciences, Humanities and Arts. His research examines social psychological processes as applied to health. This is the second of two parts.

Theoretical physics Professor Ajay Gopinathan has been working over the past decade to model a submicroscopic mystery. Now, he and a team of colleagues have verified an important piece of the puzzle of how tiny, intrinsically twisted protein filaments responsible for repairing and growing cells know where to go to perform their function.

The work could someday enable scientists to control bacterial growth.

Professor Matthew Zawadzki is with the Department of Psychological Sciences in the School of Social Sciences, Humanities and Arts. His research examines social psychological processes as applied to health. This is the first of a two-part discussion.

A UC Merced researcher and her lab have unlocked one of the mysteries that could lead to treatments — or even cures — for prion diseases in mammals.

Prion diseases are a family of rare, progressive neurodegenerative disorders that affect both humans — such as with Creutzfeldt-Jakob disease or fatal familial insomnia — and animals, such as mad-cow disease. These disorders are usually rapidly progressive and always fatal, according to the Centers for Disease Control.

Breakthrough collaborative science by an interdisciplinary team of researchers brought together by computational biology Professor David Ardell promises a new approach for treating all types of infections.

Infections have become more dangerous in recent years because bacteria and parasites rapidly evolve resistance to the medicines.

Bioengineering Professor Victor Muñoz has answered a long-standing genetic mystery, and his research suggests that someday, bioengineers could devise ways to control gene activity — manually switching off the genes that contribute to cancer, for instance.

“If this mechanism turns out to be as powerful as we anticipate, engineering it will be relatively straightforward,” Muñoz said. “Controlling the output of genes could be done in a targeted way by new genome editing technologies such as CRISPR.”

Professor Joel Spencer was a rising star in college soccer and now he is an emerging scientist in the world of biomedical engineering, capturing — for the first time — an image of a hematopoietic stem cell (HSC) within the bone marrow of a living organism.

Many faculty members are experts in their fields, pioneering new ways to think about complex subject matter. But how does one communicate that research in a simple way, specifically when seeking funding to further their research? That’s where the Office of Research Development steps in.