Biological Sciences

Many of the items people use in their everyday lives, from baby clothes and Halloween costumes to furniture, are doused with chemical flame retardants designed to make the items safer.

Breakthrough collaborative science by an interdisciplinary team of researchers brought together by computational biology Professor David Ardell promises a new approach for treating all types of infections.

Infections have become more dangerous in recent years because bacteria and parasites rapidly evolve resistance to the medicines.

Bioengineering Professor Victor Muñoz has answered a long-standing genetic mystery, and his research suggests that someday, bioengineers could devise ways to control gene activity — manually switching off the genes that contribute to cancer, for instance.

“If this mechanism turns out to be as powerful as we anticipate, engineering it will be relatively straightforward,” Muñoz said. “Controlling the output of genes could be done in a targeted way by new genome editing technologies such as CRISPR.”

Professor Joel Spencer was a rising star in college soccer and now he is an emerging scientist in the world of biomedical engineering, capturing — for the first time — an image of a hematopoietic stem cell (HSC) within the bone marrow of a living organism.

Proteins are miniscule machines inside the body, about 10,000 times smaller than the thickness of human hair. They control all the processes of life — like how cells communicate to each other, how the immune system combats infection, how muscles contract, and how oxygen is picked up in the lungs and delivered to those very same muscles.

Professor Jing Xu and her students study extremely tiny motor proteins, but their work could make a huge contribution to the growing body of knowledge about Alzheimer’s and other diseases that progressively destroy brain tissue.

Soil biogeochemistry Professor Asmeret Asefaw Berhe has been named the Ted and Jan Falasco Chair in Earth Sciences and Geology.

“The Falasco family is engaged in construction and development, so they have an intimate connection with and an understanding of the earth beneath our feet,” Berhe said. “Not only are they generous with their hard-earned resources, they are investing in a worthy cause for the Valley. They appreciate how invested we all should be in the land and the Earth.”

Professor Clarissa Nobile has been named the newest Kamangar Family Endowed Chair in Biological Sciences and will be honored at a private ceremony with the donors this fall.

“I am so pleased and honored to have been named to this chair,” Nobile said. “Thank you for investing in me and the future of biomedical research on infectious diseases at UC Merced.”

UC Merced is offering the opportunity for Valley residents to learn what clinicians and researchers know about Valley fever, an airborne fungal infection that can have serious, even fatal, consequences for people across California and the Southwest.

A multi-campus Valley fever summit in the California Room at UC Merced on Oct. 25 is free and open to all who reserve seats online by 5 p.m. Oct. 15.

Developmental biologist Professor Anna Beaudin and her lab are making breakthrough discoveries in a growing field of research that could lead to exciting developments in such medical puzzles as cancer treatments, regenerative medicine and the cause of autism.

She examines the mechanisms of how distinct blood stem cells are established during fetal development, how and why they give rise to the cells that make up human immune systems, how these cells work and what happens when something goes wrong.