Health

Theoretical physics Professor Ajay Gopinathan has been working over the past decade to model a submicroscopic mystery. Now, he and a team of colleagues have verified an important piece of the puzzle of how tiny, intrinsically twisted protein filaments responsible for repairing and growing cells know where to go to perform their function.

The work could someday enable scientists to control bacterial growth.

A UC Merced researcher and her lab have unlocked one of the mysteries that could lead to treatments — or even cures — for prion diseases in mammals.

Prion diseases are a family of rare, progressive neurodegenerative disorders that affect both humans — such as with Creutzfeldt-Jakob disease or fatal familial insomnia — and animals, such as mad-cow disease. These disorders are usually rapidly progressive and always fatal, according to the Centers for Disease Control.

Smokers and former smokers are not only more susceptible to COVID-19, they are far more likely to see their conditions worsen over time and to require intensive respiratory assistance, according to a review released Thursday by the UC Merced Nicotine and Cannabis Policy Center (NCPC).

Furthermore, the health risks may be heightened for people exposed to secondhand smoke and secondhand vaping, it says.

Breakthrough collaborative science by an interdisciplinary team of researchers brought together by computational biology Professor David Ardell promises a new approach for treating all types of infections.

Infections have become more dangerous in recent years because bacteria and parasites rapidly evolve resistance to the medicines.

Bioengineering Professor Victor Muñoz has answered a long-standing genetic mystery, and his research suggests that someday, bioengineers could devise ways to control gene activity — manually switching off the genes that contribute to cancer, for instance.

“If this mechanism turns out to be as powerful as we anticipate, engineering it will be relatively straightforward,” Muñoz said. “Controlling the output of genes could be done in a targeted way by new genome editing technologies such as CRISPR.”

Competitions, showcases, career success stories and more highlight the work of the School of Engineering and its students at UC Merced’s annual celebration of National Engineers Week, Feb. 18 to 21.

E-Week is an opportunity for engineering students to share the work they do with the campus, invite some friendly competition and introduce other students and younger school children to the field. Each day carries a specific theme, from Project Palooza (a showcase for engineering clubs and organizations) to Professional Day (career advice and alumni success stories).

Professor Joel Spencer was a rising star in college soccer and now he is an emerging scientist in the world of biomedical engineering, capturing — for the first time — an image of a hematopoietic stem cell (HSC) within the bone marrow of a living organism.

Many faculty members are experts in their fields, pioneering new ways to think about complex subject matter. But how does one communicate that research in a simple way, specifically when seeking funding to further their research? That’s where the Office of Research Development steps in.

Chia Thao was a teenager when she arrived in Fresno with her family to begin a new life. She was born in a refugee camp in Thailand, where her Laotian parents had fled after the Vietnam War.

“Our parents brought a skillset to the U.S., found a home in the Central Valley and began farming,” Thao said. “This connected them back to their homeland.”

Over the years, she witnessed the challenges small-scale farmers faced and it prompted her research interests. Now, she is using her cultural knowledge of her community to help improve health outcomes.

Proteins are miniscule machines inside the body, about 10,000 times smaller than the thickness of human hair. They control all the processes of life — like how cells communicate to each other, how the immune system combats infection, how muscles contract, and how oxygen is picked up in the lungs and delivered to those very same muscles.