CREST Center for Cellular and Biomolecular Machines

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‘Molecular LEGO’ Study Analyzes Building Blocks of Partially Disordered Protein

Bioengineering Professor Victor Muñoz and his lab have created a new way to solve some of the mysteries among an increasingly important class of proteins that don’t appear to have any specific structures but serve very important functions, including the complex genetic processes that separate high-order organisms from single-cell bacteria.

They call it “molecular LEGO,” pulling the proteins apart and rebuilding them, segment by segment.

Bioengineer Invited to Join NIH Review Board

The National Institutes of Health (NIH) have invited bioengineering Professor Eva De Alba Bastarrechea to serve as a member of the Macromolecular Structure and Function C Study Section within the Macromolecular Biophysics and Biological Chemistry Review Branch.

McCloskey Earns a Place Among Fellows in Prestigious Bioengineering Organization

The American Institute for Medical and Biological Engineering (AIMBE) has elected founding faculty member Professor Kara McCloskey into its College of Fellows for outstanding contributions to biomaterials for cell and tissue engineering, and meritorious commitment to diversity, equity and inclusion.

She is the first faculty member from UC Merced to earn this honor.

Gopinathan Chosen for Leadership Role in American Physical Society

Professor Ajay Gopinathan has been elected the next vice-chair of the Division of Biological Physics (DBIO) of the American Physical Society (APS), the world's largest organization of physicists. He will serve as vice-chair in March 2023, then move into the positions of chair-elect, chair and past chair, each for one year.

UC Merced Leaps Up in Nature Index’s Young University Rankings

UC Merced has earned the distinction of ranking No. 20 among the world's Rising Young Universities, according to the just-released Nature Index 2021 Young Universities — the only U.S. institution to place in the top 25.

Among the leading 150 Young Universities, UC Merced ranks No. 80, and for Leading 50 Young Universities in Life Sciences, it ranks No. 43. These rankings are a jump from 2019, when the campus placed No. 92 among Top 175 Young Universities.

NSF Awards CCBM Center $5 Million to Continue STEM Research

UC Merced’s NSF-CREST Center for Cellular and Biomolecular Machines (CCBM) has been awarded an additional $5 million from the National Science Foundation (NSF) to continue its mission. In total, the NSF has invested $10 million in the center, an indicator of the importance of the Center’s work and its faculty, student and staff contributions.

Scientists Assemble a Biological Clock in a Test Tube to Study How It Works

Daily cycles in virtually every aspect of our physiology are driven by biological clocks (also called circadian clocks) in our cells. The cyclical interactions of clock proteins keep the biological rhythms of life in tune with the daily cycle of night and day, and this happens not only in humans and other complex animals but even in simple, single-celled organisms such as cyanobacteria.

Chemistry Lab Receives NSF Funding to Study How Proteins Protect from Dehydration

Like many people this summer, Professor Shahar Sukenik has dehydration on his mind.

But it’s not the soaring outside temperatures prompting this focus. Dehydration has been a theme of his lab’s work for the past year, from understanding how seeds know when to germinate to a new grant to further knowledge about the proteins that help protect cells and organisms against irreversible drying.

Engineering Professor Awarded $1 Million NSF Award to Study Protein Folding

Proteins operate like biological machines, regulating nearly every major function and organ in our bodies through a still-mysterious shape-shifting process. Bioengineering graduate group chair Professor Victor Muñoz has a new $1,082,356 award from the National Science Foundation to unlock those mysteries.

Improved Molecular Tool Deepens Study of Gene-Cell Interaction

A group of researchers harnessing the power of light to control gene expression has dramatically improved its method, optimizing speed and precision, and opening new research avenues for scientists who employ optogenetics — the use of light and genetic engineering to control cells.

A new paper in the journal Zebrafish details the advancements made in Professor Stephanie Woo’s lab and quantifies the results of experiments on zebrafish embryos.