$3.5 Million Hellman Endowment Expands Future of Research at UC Merced

Since 2011, the Hellman Fellows Fund has provided close to 60 UC Merced assistant professors with much-needed research support in the form of seed funding. The prestigious Hellman Fellowship has launched countless careers at UC Merced and across the UC system.

Now, thanks to a generous new $3.5 million gift from the Hellman family, UC Merced will permanently establish the UC Merced Society of Hellman Fellows starting in 2021. The endowment allows the program to continue in perpetuity, while affording the campus more flexibility in funding early-career research.

New Project Aims to Advance Understanding of Immune Cells as they Develop

Maybe now more than ever, scientists need to understand the immune system.

A new National Institutes of Health grant is funding a cross-disciplinary collaboration between bioengineering Professor Joel Spencer and immunology Professor Jennifer Manilay that will allow them to watch as immune-system cells develop in the bone marrow of a living mouse to gain insights into how they work.

Study Reveals How Chemicals in Flame Retardants Interfere with Brain Development

Many of the items people use in their everyday lives, from baby clothes and Halloween costumes to furniture, are doused with chemical flame retardants designed to make the items safer.

Researchers Forge a New Weapon to Fight Parasites and Other Infections

Breakthrough collaborative science by an interdisciplinary team of researchers brought together by computational biology Professor David Ardell promises a new approach for treating all types of infections.

Infections have become more dangerous in recent years because bacteria and parasites rapidly evolve resistance to the medicines.

Researchers Discover Mechanism Proteins Use To Find And Control Genes

Bioengineering Professor Victor Muñoz has answered a long-standing genetic mystery, and his research suggests that someday, bioengineers could devise ways to control gene activity — manually switching off the genes that contribute to cancer, for instance.

“If this mechanism turns out to be as powerful as we anticipate, engineering it will be relatively straightforward,” Muñoz said. “Controlling the output of genes could be done in a targeted way by new genome editing technologies such as CRISPR.”

Breakthrough in Stem Cell Research: First Image of Niche Environment

Professor Joel Spencer was a rising star in college soccer and now he is an emerging scientist in the world of biomedical engineering, capturing — for the first time — an image of a hematopoietic stem cell (HSC) within the bone marrow of a living organism.

Engineered Protein Assemblies that Respond to Cues Open Path for Smart, Protein-Based Medicines

Proteins are miniscule machines inside the body, about 10,000 times smaller than the thickness of human hair. They control all the processes of life — like how cells communicate to each other, how the immune system combats infection, how muscles contract, and how oxygen is picked up in the lungs and delivered to those very same muscles.

Lab Works to Understand Molecular Motors and Cholesterol’s Relation to Alzheimer’s

Professor Jing Xu and her students study extremely tiny motor proteins, but their work could make a huge contribution to the growing body of knowledge about Alzheimer’s and other diseases that progressively destroy brain tissue.

Berhe Named to Endowed Chair in Recognition of Her Work in Soil Sciences

Soil biogeochemistry Professor Asmeret Asefaw Berhe has been named the Ted and Jan Falasco Chair in Earth Sciences and Geology.

“The Falasco family is engaged in construction and development, so they have an intimate connection with and an understanding of the earth beneath our feet,” Berhe said. “Not only are they generous with their hard-earned resources, they are investing in a worthy cause for the Valley. They appreciate how invested we all should be in the land and the Earth.”