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Molecular scale machines have implications in areas ranging from drug delivery to information storage and processing, and hold the promise of new capabilities in bottom-up nanoscale assembly similar to that of biological motors.
Professor Ye's research engineers molecules and their nanoscale environments for programmable linear motions using surface chemistry tools, such as:
In addition, his lab is developing new methods in the detection and analysis of single-molecule biopolymers.
Professor Te's lab also employs atomic force microscopy to trap and to manipulate DNA molecules through nanopores. This will enable single-molecule force spectroscopy, a technique that can provide unique insights into conformations of single biopolymers and the sequence specific information.
