Professor Ortiz's research focuses on the regulation of kidney function and metabolism in a variety of animal models, including seals and dolphins, with the intent that the data will have translative value to clinical medicine. These studies are conducted in collaboration with colleagues at:
His lab — in conjunction with collaborators at Kagawa Medical University, SUNY Buffalo Medical School, and Tulane University HSC — investigate:
Professor Ortiz is also pursuing studies that address the link between diabetes and obesity with hypertension.
From an evolutionary perspective, he is interested in the physiological mechanisms marine-adapted vertebrates use to regulate water and electrolytes during a variety of altered environmental conditions, such as prolonged food deprivation or extended fresh water exposure.